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Chlovalicin

SKU: orb3024277

Description

Chlovalicin is found in the [Streptomyces] FO-4649 strain. In the presence of 0.2 U/mL IL-6, Chlovalicin inhibits the growth of IL-6-dependent MH60 cells with an IC50 of 7.5 μM. It also suppresses the proliferation of B16 melanoma cells, exhibiting an IC50 of 38 μM. Additionally, Chlovalicin shows inhibitory activity against osteoclastogenesis.

Images & Validation

Key Properties

CAS Number179799-38-3
MW332.82
FormulaC16H25ClO5
SMILESO[C@]1([C@](CCl)(O)CCC(=O)[C@H]1OC)[C@]2(C)[C@@H](CC=C(C)C)O2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information