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Welcome to Biorbyt Custom Services—your dedicated contract research partner for bespoke antibody development, protein expression, and peptide synthesis. When off-the-shelf catalog reagents do not meet your exact target requirements, our experienced scientific team collaborates with you to design, express, purify, and characterize customized biological tools tailored to your unique experimental specifications.
From custom hybridoma generation and rabbit monoclonal antibodies to multi-system recombinant protein production and dye conjugation, our quality-controlled workflows accelerate discovery across basic research, diagnostics, and therapeutic development.
Our Custom Research Services
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VHH Antibody Production
Develop high-affinity single-domain camelid antibodies (VHH fragments/nanobodies) offering exceptional thermal stability, solubility, and structural access to cryptic or hidden protein clefts. Our end-to-end VHH production platform includes llama/alpaca immunization, phage display library construction, high-throughput screening, and recombinant expression.
Membrane & ECD Expression
Overcome traditional expression bottlenecks with specialized protocols designed to produce native full-length multi-pass membrane proteins (such as GPCRs and ion channels) as well as challenging extracellular domains (ECDs). We utilize advanced detergent micelle, nanodisc, and liposome technologies to preserve conformational integrity and biological activity.
Protein Immunology Detection
Access comprehensive protein immunology detection workflows including Western Blot (WB), Co-Immunoprecipitation (Co-IP), EMSA shift assays, Coomassie staining, and quantitative optical densitometry analysis.
Pathology Testing Services
Comprehensive histopathology solutions covering tissue embedding, microtome sectioning, H&E and special staining, single/multiplex IHC, immunofluorescence, FISH, confocal imaging, and full digital pathology reporting.
Molecular Biology Services
Accelerate your genomic and microbiological research with microbial isolation and susceptibility testing, DNA/RNA extraction, qPCR, ChIP/RIP interaction assays, custom ELISA development, and gene modification workflows.
Cell Biology Services
Integrated cell biology capabilities spanning primary cell isolation, stable monoclonal cell line selection, CCK-8/MTT proliferation assays, wound healing/invasion profiling, flow cytometry, and dual-luciferase reporter assays.
Animal Models & Technical Services
Complete preclinical modeling support featuring basic animal husbandry and dosing, CDX/PDX tumor xenografts, physiological disease models, behavioral test batteries, multimodal small animal imaging, and non-GLP pharmacology.
Recombinant Protein Expression
Accelerate your research with high-yield recombinant protein production across E. coli, yeast, baculovirus/insect, and mammalian systems (CHO and HEK293).
Peptide Synthesis
Order high-purity custom peptides (>98%) with flexible modifications—including phosphorylation, methylation, biotinylation, disulfide bridges, and isotope labeling.
Antibody Engineering
Tailor antibody affinity, specificity, and pharmacokinetics with humanization, affinity maturation, isotype/class switching, Fc silencing, and scFv/Fab fragment conversion.
Rabbit Monoclonal Antibodies
Harness the superior immune response of rabbits to generate monoclonal antibodies with exceptionally high affinity—ideal for difficult epitopes and clinical IHC.
Recombinant Antibodies
Convert existing clones into sequence-defined recombinant antibodies to permanently eliminate genetic drift, ensure reproducibility, and support animal-free research.
Monoclonal Antibodies
Access end-to-end custom mouse and rat hybridoma development, from antigen design and immunization to high-throughput ELISA screening and purification.
Polyclonal Antibodies
Generate robust, multi-epitope recognizing polyclonal antibodies in rabbit, goat, chicken, or rat hosts with custom peptide design and affinity purification.
Antibody Conjugation
Seamlessly conjugate your primary antibodies to HRP, alkaline phosphatase, biotin, or a broad spectrum of fluorophores for direct detection in flow cytometry and ELISA.