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COX-2/15-LOX-IN-6

SKU: orb2814387

Description

COX-2/15-LOX-IN-6 (Compound 5l) is a dual cyclooxygenase-2 and 15-lipoxygenase inhibitor with respective IC50 values of 0.201 µM and 11.723 µM. It reduces pro-inflammatory mediators like PGE2 and cytokines in vitro and shows in vivo efficacy in a carrageenan-induced rat paw edema model, supporting its use in inflammation research.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience

Images & Validation

Key Properties

MW552.64
FormulaC31H28N4O4S
TargetLipoxygenase,COX

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information