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Description
Research Area
Epigenetics and Nuclear Signaling
Images & Validation
−
Item 1 of 3
| Tested Applications | ICC, IF, IHC-Fr, IHC-P, WB |
|---|---|
| Dilution Range | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:50-200, IF=1:100-500 |
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Mouse |
Related Conjugates & Formulations
−Key Properties
−| Antibody Type | Primary Antibody |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated synthetic peptide derived from mouse ER-alpha (501-600/600aa) |
| Target | ESR1 |
| Molecular Weight | 66 kDa |
| Purification | Affinity purified by Protein A |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−ER; ESR; ESRA; ESTRR; Era; NR3A1; ER-alpha; ERalpha; Estr; Estra; RNESTROR; ESR1_FELCA; ESR1; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1; ESR1_HORSE; ESR1_HUMAN; ESR1_MOUSE; ESR1_PIG; ESR1_RAT; estrogen receptor 1; estrogen receptor alpha; oestrogen receptor alpha; E2 receptor alpha
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Quality Guarantee
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Quick Database Links
Gene Symbol
ESR1
UniProt
UniProt Details
− No UniProt data available
Protocol Information
WB
Western Blot (IB, immunoblot)
IHC-P
Immunohistochemistry Paraffin
IHC-Fr
Immunohistochemistry Frozen
IF
Immunofluorescence
ICC
Immunocytochemistry
Filter by Applications
Filter by Species
Ahmed M Darwesh, Mona F El-Azab, Noha M Abo-Gresha, Norhan M El-Sayed, Yasser M Moustafa Cardioprotective Mechanisms of Exenatide in Isoprenaline-induced Myocardial Infarction: Novel Effects on Myocardial α-Estrogen Receptor Expression and IGF-1/IGF-2 System Journal of Cardiovascular Pharmacology, 71, 160 (2018)
Applications
IHC
Reactivity
Rat
Wu, Yingxi et al. Downregulation of G‑protein‑coupled receptor 30 in the hippocampus attenuates the neuroprotection of estrogen in the critical period hypothesis Mol Med Rep, 17, 5716-5725 (2018)
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