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Gem-C12

SKU: orb3210894

Description

Gem-C12 is a prodrug of Gemcitabine. It halts DNA strand extension, inhibits nucleic acid synthesis, and induces apoptosis (Apoptosis). Gem-C12 effectively inhibits the proliferation of glioma cells. In combination with Honokiol, it demonstrates synergistic anti-glioblastoma activity. Gem-C12 is applicable for studies related to glioblastoma multiforme.

Images & Validation

Key Properties

CAS Number849139-19-1
MW445.50
FormulaC21H33F2N3O5
SMILESFC1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(CCCCCCCCCCC)=O)C=C2
TargetDNA/RNA Synthesis,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information