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HPK1 ligand-Linker Conjugate 1

SKU: orb3136649

Description

HPK1 ligand-Linker Conjugate 1 is a synthetic target protein ligand-linker compound used in the synthesis of PROTACs, such as PROTACHPK1 Degrader-5. PROTACHPK1 Degrader-5 is a potent and orally active HPK1 PROTAC degrader with anti-tumor activity.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number3061690-80-7
MW435.45
FormulaC19H21N3O7S
SMILESO=C1N(C(=O)C=2C1=CC(=CC2)N3C[C@H](COS(C)(=O)=O)CC3)C4C(=O)NC(=O)CC4
TargetTarget Protein Ligand-Linker Conjugates,MAPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information