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Human interleukin 6 (IL-6) 29-212 aa

SKU: orb1729595

Description

Interleukin-6 (IL-6) is a 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis and bone metabolism. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse IL-6. Aberrant IL-6 activity contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis.

Research Area

Immunology & Inflammation

Images & Validation

Tested ApplicationsSDS-PAGE
Application Notes
For research use only

Key Properties

SourceE.coli
Species/HostE. coli
Expression SystemIntercellular
Biological OriginRecombinant protein expressed as His tage protein in E.coli
ReactivityHuman, Mouse
TagHistidine
EndotoxinsNot tested
ConjugationUnconjugated
MW~22 kDa
Purity≥85%
Protein SequenceVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM

Storage & Handling

StorageAfter reconstitution, store at -20°C; Avoid repeated freeze thaw
Form/AppearanceLyophilized
Buffer/PreservativesNo preservative
Concentration1mg/mL
Expiration Date6 months from date of receipt.
Hazard InformationFor Research use only
DisclaimerFor research use only

Alternative Names

B-cell stimulatory factor 2 (BSF-2), CTL differentiation factor (CDF), Hybridoma growth factor
Quality Guarantee

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UniProt Details

No UniProt data available

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide
SDS-PAGE
Sodium Dodecyl Sulphate PolyAcrylamide Gel Electrophoresis
View Protocol

Available Sizes

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100 μg
$ 550.00
DispatchUsually dispatched within 5-10 working days
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