Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

IDH1 Inhibitor 1

SKU: orb1709444

Description

IDH1 Inhibitor 1 is a potent, selective, and orally bioavailable small molecule targeting mutant IDH1R132H/C with high selectivity over the wild-type enzyme. Its brain-penetrant properties make it a valuable tool for investigating mutant IDH1-driven mechanisms in cancers like glioma, both in cellular assays and in vivo models.

Research Area

Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2234285-81-3
MW450.39
FormulaC20H18F4N6O2
SMILESC[C@H](Nc1nccc(n1)N1[C@@H](CF)COC1=O)c1cn(cn1)-c1ccc(cc1)C(F)(F)F
TargetIsocitrate Dehydrogenase (IDH),Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Olutasidenib [orb3033169]

    >98%

    1887014-12-1

    354.8

    C18H15ClN4O2

    5 mg, 25 mg
  • DS-1001b [orb1299547]

    >99.99% (May vary between batches)

    1898207-64-1

    608.92

    C29H29Cl3FN3O4

    1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO), 200 mg
  • Mutant IDH1-IN-1 [orb1306660]

    >99.99% (May vary between batches)

    1355326-21-4

    498.59

    C30H31FN4O2

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)
  • Olutasidenib [orb1307932]

    99.59% (May vary between batches)

    1887014-12-1

    354.79

    C18H15ClN4O2

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 mg, 1 ml x 10 mM (in DMSO), 200 mg
  • Mutant IDH1 inhibitor [orb1308000]

    98.30% (May vary between batches)

    1429180-08-4

    466.58

    C25H34N6O3

    1 mg, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg, 25 mg, 1 ml x 10 mM (in DMSO)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information