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JH-FK-08

SKU: orb2945367

Description

JH-FK-08 is a calcineurin phosphatase inhibitor with dual antifungal and immunosuppressive activities. It demonstrates potent in vitro efficacy against Cryptococcus neoformans and suppresses IL-2 expression, supported by anti-infective activity observed in mouse models.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

MW864.073
FormulaC45H73N3O13
SMILESCC[C@@H]\1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](C/C1=N/NC(=O)OC)O)C)/C(=C/C4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)\C
TargetInterleukin,Antifungal

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information