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LBP-14

SKU: orb3212264

Description

LBP-14 is a peptide and a synthetic fragment of LPS-binding protein (LBP), also functioning as an LPS antagonist. It interacts with LPS through electrostatic attraction between arginine/lysine residues and LPS phosphate groups, as well as hydrophobic interactions between aromatic/aliphatic residues and LPS acyl chains, thus blocking the binding of LPS to LBP. LBP-14 can moderately inhibit the production of TNF-α stimulated by LPS. It is useful for research related to Gram-negative bacterial sepsis.

Images & Validation

Key Properties

TargetAntibacterial
CAS Number324030-22-0
MW1765.07
FormulaC82H129N27O17
SMILESC([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)CO)=O)C)=O)CCCNC(=N)N)=O)[C@H](C)C)=O)CCCCN)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)C(C)C)=O)CCC(N)=O)=O)=O)CCCNC(=N)N)=O)C=3C=4C(NC3)=CC=CC4

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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