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Lenalidomide-Br

SKU: orb1218478

Description

Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC STAT3 degrader SD-36.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2093387-36-9
MW323.14
Purity>98% (HPLC)
FormulaC13H11BrN2O3
SMILESO=C(C(N(CC1=C2C=CC=C1Br)C2=O)CC3)NC3=O
TargetPROTAC
SolubilityDMSO : 30 mg/mL (92.84 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information