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Ligustilide

SKU: orb1301294

Description

Ligustilide

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number4431-01-0
MW190.24
Purity99.97% (May vary between batches)
FormulaC12H14O2
SMILESCCC1(C)C2OC(=O)C3C=CCCC123
TargetAutophagy,Apoptosis
SolubilityDMSO:1.91 mg/mL (10.04 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (5.26 mM)

Bioactivity

In Vitro
To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide .

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, inhibit, Ligustilide, Apoptosis, Autophagy

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 80.00
5 mg
$ 120.00
10 mg
$ 140.00
25 mg
$ 210.00
50 mg
$ 290.00
100 mg
$ 410.00
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