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Manumycin A

SKU: orb1707014

Description

Manumycin A is a thioredoxin reductase-1 (TrxR-1) inhibitor with antibiotic and anticancer properties. It induces apoptosis and suppresses pro-inflammatory cytokine production (IL-1β, IL-6, IL-8) in stimulated immune cells, as demonstrated in vitro with THP-1 and PBMC models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number52665-74-4
MW550.64
FormulaC31H38N2O7
SMILES[H][C@]12O[C@@]1([H])[C@](O)(\C=C\C=C\C=C\C(=O)NC1=C(O)CCC1=O)C=C(NC(=O)C(\C)=C\C(\C)=C\[C@H](C)CCCC)C2=O
TargetATG,Antibiotic,TNF,Transferase,Reductase,Apoptosis,Phospholipase,Ras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 470.00
5 mg
$ 1,430.00
DispatchUsually dispatched within 5-10 working days
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