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Description
Research Area
CARdiovascular Research, Cell Biology, Mitochondrial Markers
Images & Validation
−
Item 1 of 1
| Tested Applications | ELISA, ICC, IF, IHC-Fr, IHC-P, WB |
|---|---|
| Dilution Range | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 |
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Bovine, Canine, Equine, Human, Porcine, Rabbit, Sheep |
Related Conjugates & Formulations
−Key Properties
−| Antibody Type | Primary Antibody |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | KLH conjugated synthetic peptide derived from human MCU (251-351//351aa) |
| Target | MCU |
| Molecular Weight | 42 kDa |
| Purification | Affinity purified by Protein A |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | Preservative: 0.02% Proclin300, Constituents: 1% rAlbumin, 0.01M PBS, pH 7.4. |
| Concentration | 1mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−C10orf42; CCDC109A; HsMCU; 2010012O16Rik; D130073L02Rik; Gm64; MCU_HUMAN; MCU; Coiled-coil domain-containing protein 109A; MCU_MOUSE; mitochondrial calcium uniporter; coiled-coil domain containing 109A
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Quick Database Links
Gene Symbol
MCU
UniProt
UniProt Details
− No UniProt data available
Protocol Information
WB
Western Blot (IB, immunoblot)
IHC-P
Immunohistochemistry Paraffin
IHC-Fr
Immunohistochemistry Frozen
IF
Immunofluorescence
ICC
Immunocytochemistry
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
Filter by Applications
Filter by Species
Ziqing Yu, Ruizhen Chen, Minghui Li, Yong Yu, Yixiu Liang, Fei Han, Shengmei Qin, Xueying Chen, Yangang Su, Junbo Ge Mitochondrial calcium uniporter inhibition provides cardioprotection in pressure overload-induced heart failure through autophagy enhancement International Journal of Cardiology, 271, 161 (2018)
Applications
IHC
Reactivity
Mouse
Yu, Ziqing et al. The mechanical effects of CRT promoting autophagy via mitochondrial calcium uniporter down-regulation and mitochondrial dynamics alteration J. Cell. Mol. Med., (2019)
Applications
IF, WB
Reactivity
Canine
Available Sizes
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