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Miconazole

SKU: orb1225592

Description

Miconazole (Monistat) is an imidazole antifungal agent.(In Vitro):Miconazole is an imidazole antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa which are a type of unicellular parasite that also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some antibacterial properties. Miconazole is also used in Ektachrome film developing in the final rinse of the Kodak E-6 process and similar Fuji CR-56 process, replacing formaldehyde. Fuji Hunt also includes miconazole as a final rinse additive in their formulation of the C-41RA rapid access color negative developing process.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number22916-47-8
MW416.13
Purity>98% (HPLC)
FormulaC18H14Cl4N2O
SMILESClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
TargetAntifection
SolubilityEthanol: 83 mg/mL (199.45 mM); DMSO: 83 mg/mL (199.45 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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