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MK-3207

SKU: orb2664844

Description

MK-3207 is a potent, orally bioavailable CGRP receptor antagonist with sub-nanomolar affinity (Ki = 0.024 nM) for the human receptor and high selectivity. It effectively blocks CGRP-induced dermal vasodilation in vivo, making it a valuable research tool for studying migraine pathophysiology and neurogenic inflammation in preclinical models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number957118-49-9
MW557.59
FormulaC31H29F2N5O3
SMILESO=C1[C@@]2(C=3C(N1)=NC=CC3)CC=4C(C2)=CC=C(NC(CN5[C@@H](CNC6(C5=O)CCCC6)C7=CC(F)=CC(F)=C7)=O)C4
TargetCGRP Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

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10 mg
$ 570.00
DispatchUsually dispatched within 5-10 working days
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