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NLRP3-IN-49

SKU: orb2665076

Description

NLRP3-IN-49 (Z48) is a specific NLRP3 inflammasome inhibitor, binding directly to NLRP3 (Kd=1.05 µM) and blocking its assembly. It shows potent activity in cellular models like THP-1 cells and BMDMs and is used in research for inflammatory diseases such as inflammatory bowel disease.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

TargetNOD-like Receptor (NLR)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information