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NLRP3-IN-51

SKU: orb2664871

Description

NLRP3-IN-51 (Compound 3q) is a cholinergic anti-inflammatory pathway (CAP) activator that inhibits MSU-induced IL-1β production in THP-1 cells and suppresses NF-κBp65 phosphorylation. It demonstrates potential for gouty arthritis research by targeting upstream inflammasome signaling without directly affecting NLRP3 or caspase-1 activation.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

TargetNF-κB

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information