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NLRP3-IN-79

SKU: orb3135010

Description

NLRP3-IN-79 (Compound B6) is a selective inhibitor of the NLRP3 inflammasome with an IC50 value of 10.69 nM. It blocks the assembly of the NLRP3 inflammasome by disrupting the interaction between NEK7 and NLRP3. NLRP3-IN-79 shows potential for research in NLRP3-driven inflammatory diseases such as systemic inflammation, peritonitis, and colitis.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

TargetMAPK,NOD-like Receptor (NLR)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information