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p38 Kinase inhibitor 7

SKU: orb2944992

Description

p38 Kinase inhibitor 7 (Comp:XXXIX) is a potent and selective p38α inhibitor with an IC50 of 5.25 nM. It effectively blocks TNFα production in THP-1 cells (IC50 = 5.88 nM), making it a valuable tool for researching inflammation and autoimmune diseases in cellular models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number815595-14-3
MW408.472
FormulaC22H25FN6O
SMILESFC1=CC=C(C=C1)C=2N=C3OC=CN3C2C=4N=C(N=CC4)NCC(C)(C)CN(C)C
Targetp38 MAPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information