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Pentamidine

SKU: orb1305716

Description

Pentamidine is an antifungal and antiprotozoal agent that binds the minor groove of AT-rich duplex DNA, inhibiting replication. It is widely used in research for studying trypanosomiasis, Pneumocystis pneumonia, and other infections in both in vitro and in vivo experimental models.

Research Area

Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number100-33-4
MW340.42
Purity99.67% (May vary between batches)
FormulaC19H24N4O2
SMILESC(=N)(N)C1=CC=C(OCCCCCOC2=CC=C(C(=N)N)C=C2)C=C1
TargetAntifungal,Antibacterial,Phosphatase,Parasite,Antibiotic
SolubilityDMSO:Slightly soluble

Bioactivity

Target IC50
Leishmania infantum:2.5 μM (IC50)
In Vitro
Pentamidine is effective in therapy for the hemolymphatic stage of Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Bacterial, arrest, Antibiotic, antitumor, antifungal, carinii, biosynthetics, cell-cycle, DNA, MP601205, MP-601205, MP 601205, Kidney, inhibit, Parasite, Fungal, Inhibitor, PTP1B, Pneumocystis, pneumonia, Pentamidine, Phosphatase

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

10 mg
$ 70.00
25 mg
$ 100.00
50 mg
$ 130.00
100 mg
$ 160.00
200 mg
$ 220.00
DispatchUsually dispatched within 5-10 working days
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