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PLpro inhibitor

SKU: orb1309231

Description

This small molecule PLpro inhibitor exhibits potent activity with an IC50 of 2.6 µM. It blocks viral polyprotein cleavage, serving as a valuable tool for in vitro coronavirus research and the study of viral replication mechanisms.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1093070-14-4
MW346.42
Purity99.82% (May vary between batches)
FormulaC22H22N2O2
SMILESC[C@@H](NC(=O)c1cc(NC(C)=O)ccc1C)c1cccc2ccccc12
TargetSARS-CoV
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.77 mM);DMSO:40 mg/mL (115.47 mM)

Bioactivity

Target IC50
PLpro:2.6 µM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, papain-like protease (PLpro), PLpro inhibitor, SARS coronavirus, SARSCoV, SARS-CoV

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 70.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 160.00
25 mg
$ 270.00
50 mg
$ 380.00
100 mg
$ 500.00
200 mg
$ 660.00
DispatchUsually dispatched within 5-10 working days
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