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SuO-Val-Cit-PAB-MMAE

SKU: orb1987698

Description

This ADC linker incorporates the cytotoxic payload MMAE, a potent tubulin inhibitor, via a protease-cleavable SuO-Val-Cit-PAB peptide sequence. It is widely used in the development of antibody-drug conjugates for targeted cancer therapy research, enabling the study of drug delivery and efficacy in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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MW1264.51
FormulaC63H97N11O16
SMILESCC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(ON4C(CCC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C
TargetPROTAC Linker,Drug-Linker Conjugates for ADC

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

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No computed properties available.

Protocol Information