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PROTAC BET Degrader-13

SKU: orb3136590

Description

PROTACBET Degrader-13 (Compound 34) is a TRIM21-based PROTAC (TRIMTAC) degrader that targets BET proteins. It effectively degrades the PML-eGFP-BRD4 fusion protein, causing a near-complete loss of EGFP+ nuclear foci with an EC50 of 1.4 μM.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetPROTACs,Epigenetic Reader Domain

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information