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(rac)-NDT-19795

SKU: orb3181839

Description

(rac)-NDT-19795 is the racemate of NDT-19795. NDT-19795 is a potent inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 66 nM in the PBMC assay and 4.7 μM in the WB assay. This compound is a carboxylic acid active substance, which can be intracellularly converted from NT-0796. NDT-19795 is applicable in studies related to inflammatory and neurological disorders.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2272918-42-8
MW367.41
FormulaC20H21N3O4
SMILESO=C(OC(C(=O)O)CC1=NC=CC=N1)NC=2C3=C(C=C4C2CCC4)CCC3
TargetNOD-like Receptor (NLR)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information