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(S)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2

SKU: orb2814349

Description

This bifunctional molecule incorporates an E3 ubiquitin ligase ligand (thalidomide-based) linked to a targeting moiety, forming the core structure of the degrader NX-2127. It is a key research tool for developing proteolysis-targeting chimeras (PROTACs) to study targeted protein degradation in both cellular and preclinical models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW515.6
FormulaC29H33N5O4
TargetE3 Ligase Ligand-Linker Conjugates

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information