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SAX-187

SKU: orb1304450

Description

SAX-187 is a potent and selective ligand for the human serotonin 5-HT6 receptor. It is a valuable tool compound for investigating the receptor's function in neuropharmacology, supporting both in vitro binding assays and in vivo behavioral studies related to cognitive disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number554403-49-5
MW380.87
Purity98.00% (May vary between batches)
FormulaC15H13ClN4O2S2
SMILESNCCc1cn(c2ccccc12)S(=O)(=O)c1c(Cl)nc2sccn12
Target5-HT Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.25 mM);DMSO:60 mg/mL (157.53 mM)

Bioactivity

Target IC50
5-HT6 receptor:2.2 nM (Ki)|5-HT6 receptor:6.6 nM (EC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Serotonin Receptor, WAY 181187, WAY181187, WAY-181187, related, SAX 187, SAX187, 5-HT Receptor, 5-HT6, 5HTReceptor, 5HT Receptor, 5-hydroxytryptamine Receptor, anxiety, cAMP, disorders, ERK1/2, Fyn, Inhibitor, OCD, inhibit

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 120.00
5 mg
$ 180.00
1 ml x 10 mM (in DMSO)
$ 190.00
10 mg
$ 270.00
25 mg
$ 400.00
50 mg
$ 570.00
100 mg
$ 860.00
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