Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

SR-THAP

SKU: orb3211454

Description

SR-THAP is a γ-aminobutyric acid transporter 3 (GAT3) inhibitor with an IC50 of 4.9 μM, demonstrating selectivity for GAT3 over GAT1 and GlyT1 by 42-fold and 23-fold respectively. It inhibits GABA uptake in mammalian cells and can be utilized in research concerning epilepsy, Alzheimer's disease, and ischemic stroke.

Images & Validation

Key Properties

CAS Number3098361-74-8
MW517.61
FormulaC31H35NO6
SMILESC(/C=C/CN1[C@@]([C@@H](C(O)=O)O)(CCC1)[H])(C2=CC=C(OC)C=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4
TargetGABA Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information