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Description
Research Area
Cancer Biology, Cell Biology, Immunology & Inflammation, Signal Transduction
Images & Validation
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Key Properties
−| Biological Activity | The ED50 was determined by TGF beta 1’s ability to inhibit the mouse IL - 4 - dependent proliferation of mouse HT - 2 cells is ≤ 0.05 ng/mL, corresponding to a specific activity of ≥ 2 x 107 units/mg |
|---|---|
| Target | TNFSF10 |
| Purity | Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
| Protein Sequence | ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS |
Storage & Handling
−| Storage | The lyophilized TGF beta 1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TGF beta 1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing TGF beta 1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
|---|---|
| Form/Appearance | Lyophilized |
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−TL2, APO2L, CD253, TRAIL, Apo-2L, Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand
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Quick Database Links
UniProt Details
− No UniProt data available
NCBI Reference Sequences
−Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product| Protein | NP_001177871.1 |
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Protocol Information
Protein Handling and Storage Guide
Protein Handling Guide
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