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CGRP antagonist 7

SKU: orb3136358

Description

CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2173508-07-9
MW529.61
FormulaC30H32FN5O3
SMILESC(CNC(=O)C1=CC(C)=C(CC=2C(=O)NN=C(C)C2)C=C1)(=O)N3[C@@H](CC[C@@H]3C(C#N)(C)C)C4=CC(F)=CC=C4
TargetCGRP Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information